| Abstrakt: |
Purpose: While the effects of sleep on cognition in typically developing children are well established, there is a paucity of research in patients with pediatric brain tumor (PBT), despite their increased risk for sleep-related disturbances. The aim of this retrospective study was to examine the impact of sleep factors on patient-reported outcome (PRO) measures, including adaptive and executive functioning within this population. Methods: 133 patients with PBT (52% male) ages 5–23 (x̄ = 12.8 years; SD = 4.5 years) underwent neuropsychological evaluation, including assessment of adaptive and executive functioning. Subjective sleep concerns, nocturnal sleep duration, and daytime sleep behavior were also collected and compared to age-based guidelines. Results: Nearly 30% of patients endorsed subjective sleep concerns, while the sample as a whole reported reduced nocturnal sleep duration (approximately one hour below age-based recommendations). Despite the expectation for monophasic sleep by age five, nearly half of the sample reported consistent daytime napping. Inadequate sleep predicted decreased adaptive functioning, F(1, 56) = 4.23, p =.022 (R2 =.07), as well as increased symptoms of executive dysfunction, F(1, 108) = 3.51, p =.003 (R2 =.03). Conclusion: Patients with PBT demonstrate several aspects of abnormal sleep, which are associated with poorer long-term PROs. Further exploration of diagnostic, treatment-related, and demographic variables will be needed to better understand these relationships among patients with PBT in order to inform appropriate interventions. [ABSTRACT FROM AUTHOR] |
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