Selective excitation enables encoding and measurement of multiple diffusion parameters in a single experiment.

Autor: MacKinnon, Neil, Alinaghian, Mehrdad, Silva, Pedro, Gloge, Thomas, Luy, Burkhard, Jouda, Mazin, Korvink, Jan G.
Předmět:
Zdroj: Magnetic Resonance; 2021, Vol. 2 Issue 2, p835-842, 8p
Abstrakt: Band selectivity to address specific resonances in a spectrum enables one to encode individual settings for diffusion experiments. In a single experiment, this could include different gradient strengths (enabling coverage of a larger range of diffusion constants), different diffusion delays, or different gradient directions (enabling anisotropic diffusion measurement). In this report, a selective variant of the bipolar pulsed gradient eddy current delay (BPP-LED) experiment, enabling selective encoding of three resonances, was implemented. As proof of principle, the diffusion encoding gradient amplitude was assigned a range dependent on the selected signal, thereby allowing the extraction of the diffusion coefficient for water and a tripeptide (Met-Ala-Ser) with optimal settings in a single experiment. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index