| Autor: |
Benam, Kambez H., Burgess, Janette K., Stewart, Alastair G. |
| Předmět: |
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| Zdroj: |
Frontiers in Pharmacology; 1/3/2022, Vol. 12, p1-3, 3p |
| Abstrakt: |
Keywords: microphysiological systems; organs-on-chips; organoids; predictive modeling; pharmacology; safety; efficacy; translational science EN microphysiological systems organs-on-chips organoids predictive modeling pharmacology safety efficacy translational science 1 3 3 01/05/22 20220103 NES 220103 The discovery of new therapeutic modalities is a lengthy and costly process ([9]). Specifically, they studied the impact of repurposed drugs, hydroxychloroquine (HCQ) or azithromycin (AZM), for treating severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Lee-Montiel I et al. i , merged stem cell biology with tissue microengineering to generate liver and cardiac MPSs derived from the same induced pluripotent stem cell (hiPSC) line, and then applied their integrated multi-Organ Chips platform to study drug-drug interactions (Lee-Montiel et al.). [Extracted from the article] |
| Databáze: |
Complementary Index |
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