Profile and Epidemiology of Intussusception in Children Under-Two Years of Age: A Prospective Surveillance.

Autor: Das, Manoja Kumar, Arora, Narendra Kumar, Mathai, John, Sam, Cenita J., G., Rajamani, R., Krishnaswamy, K., Jothilakshmi, Arunachalam, Pavai, Gupta, Bini
Zdroj: Indian Journal of Pediatrics; Dec2021, Vol. 88 Issue 12, p1187-1194, 8p
Abstrakt: Objective: To report background intussusception epidemiology in children under-two years in Coimbatore district of Tamil Nadu state, India, prior to rotavirus vaccine (RVV) introduction. Methods: Prospective sentinel surveillance was done at four hospitals in Coimbatore during April 2016 to September 2017. The children aged >1 mo and < 24 mo with diagnosed intussusception were recruited and data on clinical, treatment, diet, immunization, and sociodemography were collected. Results: Sixty-eight children with intussusception were recruited. Among them 76.5% were infants with male predominance (57.4%) and 48.5% were 4–8 mo old. Vomiting (83.8%), pain in abdomen (including excessive crying) (72.1%), and bloody stools (45.6%) were the main symptoms. Reduction was tried in 92.6% cases with success in 83.8%. Surgery was needed by 16.2% children. No child died. Any RVV dose was received by 24.1% children and 2 children received RVV in 8–21 d and none within 1–7 d window. The incidence of intussusception requiring hospitalization was estimated to be 36.4 and 11.7 cases/100,000 children/y for the first and second years, respectively. Conclusion: Intussusception occurred in infants even without RVV exposure. Continued surveillance is needed to document the changes in intussusception epidemiology after RVV introduction. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index