| Autor: |
Roring, Maya E., Nugraha, Jusak, Prasetyo, Risky V., Marpaung, Ferdy R. |
| Předmět: |
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| Zdroj: |
Indian Journal of Forensic Medicine & Toxicology; Oct-Dec2021, Vol. 15 Issue 4, p1803-1809, 7p |
| Abstrakt: |
This was an observational analytic research with cross sectional design carried out at the Clinical Pathology Laboratory and Department of Child health of the Dr. Soetomo Hospital Surabaya in April - November 2020. Urine sediment of glomerular hematuria pediatric patient examined using flowcytometry, low condenser light microscope (LLCM), phase contrast microscope (PCM). The concordance of the results of the examination of dysmorphic erythrocytes and erythrocyte cylinders using flowcytometry with PCM was determined by Cohen's Kappa Coefficient (κ) and Bland Altman. There were 40 urine samples of children with glomerular hematuria with many diagnose was lupus nephritis of 60%. The analysis of dysmorphic erythrocyte examination from LLCM and PCM had a very strong kappa agreement κ 0.828 (p <0.05); The concordance analysis of LLCM and PCM cast erythrocyte had a strong agreement, κ 0.625 (p <0.05) and the concordance analysis between Flowcitometry and PCM dysmorphic erythrocyte flagging had a weak agreement, κ 0.302 (p> 0.05). LLCM can be considered to replace PCM to determine the origin of hematuria because it is very effective in detecting dysmorphic erythrocytes in patients with glomerular hematuria. The use of automatic tools is useful for pathological urine samples, but it is advisable to review them using a manual macroscope. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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