A study of procalcitonin and c-reactive protein in chronic h.pylori gastritis and it’s relation to severity of the disease.

Autor: Makhlouf, Mohamed A. M., Salama, Mohamed M., Elessawy, Hagar A. A., Abd El-Hady, Ramy M.
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Zdroj: QJM: An International Journal of Medicine; 2021 Supplement, Vol. 114, pi195-i195, 1p
Abstrakt: Background: Gastritis is an important premalignant lesion and recent studies suggested a production of inflammatory cytokine-like C-reactive protein during gastritis. This study aimed to determine any relationship between high sensitive Creactive protein (hs-CRP) and inflammation activity among patients with gastritis. Aim and objectives: the aim of the study is to compare the levels of procalcitonin and CRP in serum between positive and negative H. pylori chronic gastritis, to correlate their levels with the severity of inflammation of chronic gastritis[h.pylori related and non h.pylori related]and to suggest any effect of different regimens of treatment and their levels in serum. Subjects and methods: This is a Cross sectional comparative study, was carried out at Internal Medicine medicine departments of Ain Shams university hospitals, from September 2019 till March 2020, on 75 patients divided into 3 groups: (Group A); positive H. Pylori chronic gastritis,(Group B); negative H. Pylori chronic gastritis,(Group C); normal control group. Results: There was positive highly significant correlation between H. Pylori severity and each of CRP and Procalcitonin where (r =0.929; P <0.001) and (r =0.928; P <0.001) respectively. Conclusion: PCT and CRP were effective markers for primary diagnosis, as well as eradication follow-up after therapy, when they were used in parallel with conventional diagnostic methods. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index