Antioxidant Properties of a Nanostructured Clathrate Complex Selenopyran with β-Cyclodextrin in Model Systems of Oxidative Stress.

Autor: Dzikovskaya, L. A., Degtyareva, E. S., Shegai, P. V., Ivanov, S. A., Kaprin, A. D.
Předmět:
Zdroj: Bulletin of Experimental Biology & Medicine; May2021, Vol. 171 Issue 2, p247-250, 4p
Abstrakt: We studied the effect of nanostructured clathrate complex 9-phenyl-symm-octahydoselenoxanthene (selenopyran) with β-cyclodextrin on the generation of ОН· radicals in the Fenton system and parameters of oxidative stress in rat liver cells incubated at 37°С for 1 h. The complex inhibits the development of free-radical oxidative processes induced by ROS and the most toxic ОН· radicals, reduces the increased level of ROS induced by prooxidants, and exhibits antioxidant activity. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index