LUNG ABSCESSES WITH FORMATION OF SEVERAL CAVITIES AND PNEUMOMEDIASTINUM AS RARE COMPLICATIONS IN COVID-19.

Autor: T. N., GHALECHYAN, H. M., MARGARYAN, N. S., STEPANYAN, M. V., DAVIDYANTS, L. G., NIAZYAN
Předmět:
Zdroj: New Armenian Medical Journal; Sep2021, Vol. 15 Issue 3, p72-77, 6p
Abstrakt: Pneumonia caused by severe acute respiratory syndrome coronavirus 2 emerged in China at the end of 2019. SARS-CoV-2 is a highly pathogenic and transmissible coronavirus that primarily spreads through respiratory droplets and close contact. A growing body of clinical data suggests that a cytokine storm is associated with COVID-19 severity and is also a crucial cause of death from COVID-19. Because of the severe immunomodulation and lymphocyte depletion caused by this virus and the subsequent administration of drugs directed at the immune system, bacterial and fungal superinfection can occur. We are presenting a case of lung abscesses developed in CoVID-19 patient as complication. We hypothesized that corticosteroid therapy administration could have predisposed the patient with COVID-19 to develop superinfection of bacterial origin leading to formation of multiple lung abscesses due to a diminished innate immune response. A lung abscess is a cavity of the pulmonary parenchyma filled with fluid caused by infection or necrotic debris. High rates of morbidity and mortality are associated with lung abscess despite appropriate antibiotic therapy and better supportive care. Clinicians have to highly consider the probability of the pulmonary abscess development in CoVID-19 patients administered the high therapeutic dosage of steroids despite the evidence of the absence of procalcitonin elevation in dynamics, intoxication signs and febrile fever. A chest computerized tomography scan has to be done even in case of a small suspicion of such complications. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index