The Effect of Mobile Radiation on the Oxidative Stress Biomarkers in Pregnant Mice.

Autor: Moghadasi, Nargess, Alimohammadi, Iraj, Variani, Ali Safari, Ashtarinezhad, Azadeh
Předmět:
Zdroj: Journal of Family & Reproductive Health; Sep2021, Vol. 15 Issue 3, p172-178, 7p
Abstrakt: Objective: Due to the growing use of communication instruments such as cell phones and wireless devices, there is growing public concern about possible harmful effects, especially in sensitive groups such as pregnant women. This study aimed to investigate the oxidative stress induced by exposure to 900 MHz mobile phone radiation and the effect of vitamin C intake on reducing possible changes in pregnant mice. Materials and methods: Twenty-one pregnant mice were divided into three groups (control, mobile radiation-exposed, and mobile radiation plus with vitamin C intake co-exposed (200 mg/kg)). The mice in exposure groups were exposed to 900 MHz, 2 watts, and a power density of 0.045 µw/cm2 mobile radiation for eight hours/day for ten consecutive days. After five days of rest, MDA (Malondialdehyde), 8-OHdG (8-hydroxy-2' -deoxyguanosine), and TAC (Total Antioxidant Capacity) levels were measured in the blood of animals. The results were analyzed by SPSS.22.0 software. Results: The results showed that exposure to mobile radiation increased MDA (P=0.002), and 8-OHdG (P=0.001) significantly and decreased Total Antioxidant Capacity in the exposed groups (P=0.001). Taking vitamin C inhibited the significant increase in MDA and 8-OHdG levels in exposed groups. Conclusion: Although exposure to mobile radiation can cause oxidative stress in the blood of pregnant mice, vitamin C as an antioxidant can prevent it. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index