Autor: |
Tiwari, Ankit, Kaweewan, Issara, Miyake, Yuto, Hemmi, Hikaru, Kodani, Shinya |
Předmět: |
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Zdroj: |
Natural Product Research; Aug2021, Vol. 35 Issue 16, p2700-2706, 7p |
Abstrakt: |
New chymotrypsin inhibitory peptides named streptopeptolins B and C were isolated from Streptomyces olivochromogenes. Structures of streptopeptolins B and C were determined to be cyclic depsipeptides possessing 3-amino-6-hydroxy-2-piperidone unit by interpretation of NMR spectra and ESI-MS. Streptopeptolins B and C showed inhibitory activities to chymotrypsin with IC50 of 8.0 and 12.0 μg/mL, respectively. [ABSTRACT FROM AUTHOR] |
Databáze: |
Complementary Index |
Externí odkaz: |
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