| Autor: |
Barthichoto, Marcela, Moretto, Thaís Ludmilla, de Carvalho, Francine Pereira, Benfato, Izabelle Dias, de Rosso, Veridiana Vera, Ribeiro, Daniel Araki, Estadella, Debora, Le Sueur-Maluf, Luciana, Pisani, Luciana Pellegrini, de Oliveira, Camila Aparecida Machado |
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| Zdroj: |
Nutrire; 4/16/2021, Vol. 46 Issue 1, p1-11, 11p |
| Abstrakt: |
Purpose: To investigate the effects of juçara pulp supplementation on energy homeostasis and metabolic complications in diet-induced obese mice. Methods: Mice received a control (C) or a high-fat diet (H) for 16 weeks and for half the diet was supplemented with 0.5% freeze-dried juçara powder (CJ and HJ groups, respectively). Food intake, body weight, energy expenditure, glucose tolerance, insulin sensitivity, liver steatosis, and uncoupling protein 1 (UCP1) expression in brown adipocytes were analyzed. Results: Juçara pulp supplementation reduced body weight gain in HJ compared to H group but increased body weight in CJ compared to C group. Energy intake was higher in the CJ group than in C, H, and HJ, but similar between H and HJ groups. Despite similar energy intake, juçara pulp supplementation increased energy expenditure in HJ compared to H group. However, UCP-1 expression was not affected by juçara. Also, H mice exhibited a severe diet-induced glucose intolerance and insulin resistance, all of which were significantly improved in HJ mice. In addition, H group had higher fat content in hepatocytes than HJ, whereas no difference was observed between C and CJ. Conclusions: Juçara pulp has a great potential to reduce the metabolic complications associated with obesity. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
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