Factors associated with sexually transmitted infections among care-seeking adults in the African Cohort Study.

Autor:	Semwogerere, Michael, Dear, Nicole, Tunnage, Joshua, Reed, Domonique, Kibuuka, Hannah, Kiweewa, Francis, Iroezindu, Michael, Bahemana, Emmanuel, Maswai, Jonah, Owuoth, John, Crowell, Trevor A., Ake, Julie A., Polyak, Christina S., Esber, Allahna, for the AFRICOS Study Group, Bartolanzo, Danielle, Reynolds, Alexus, Song, Katherine, Milazzo, Mark, Francisco, Leilani
Předmět:	SEXUALLY transmitted diseases HIV-positive persons SEXUALLY transmitted disease diagnosis DISEASE prevalence MENTAL health
Zdroj:	BMC Public Health; 4/16/2021, Vol. 21 Issue 1, p1-11, 11p, 7 Charts
Abstrakt:	Objectives: Sexually transmitted infections (STIs) are a major cause of morbidity. Understanding drivers of transmission can inform effective prevention programs. We describe STI prevalence and identify factors associated with STIs in four African countries.Methods: The African Cohort Study is an ongoing, prospective cohort in Kenya, Nigeria, Tanzania and Uganda. At enrollment, a physical exam was conducted and STI diagnosis made by a clinician using a syndromic management approach. Multivariable logistic regression was used to estimate adjusted odds ratios (aORs) and 95% confidence intervals (95% CIs) for factors associated with an STI diagnosis.Results: As of June 2020, 3544 participants were enrolled. STI prevalence was 7.7% and did not differ by HIV status (p = 0.30). Prevalence differed by syndrome (3.5% vaginal discharge, 1.5% genital ulcer, 2.1% lower abdominal pain, 0.2% inguinal bubo). The odds of having an STI were higher at all sites compared to Kisumu West, Kenya, and among those with a primary level education or below compared to those with secondary or higher (aOR: 1.77; 95% CI: 1.32-2.38). The odds of an STI diagnosis was higher among participants 18-29 years (aOR: 2.29; 95% CI: 1.35-3.87), females (aOR: 2.64; 95% CI: 1.94-3.59), and those with depression (aOR: 1.78; 95% CI: 1.32-2.38). Among PLWH, similar factors were independently associated with an STI diagnosis. Viral suppression was protective against STIs (aOR: 2.05; 95% CI: 1.32-3.20).Conclusions: Prevalence of STIs varied by site with young people and females most at risk for STIs. Mental health is a potential target area for intervention. [ABSTRACT FROM AUTHOR]
Databáze:	Complementary Index
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