| Abstrakt: |
A negative correlation between the mammalian erythrocyte lifespan (Tls, days) with increasing lifespan (mouse, guinea pig, rabbit, cat, horse, dog, human, goat, cow, sheep), and sodium, and potassium ion membrane permeability coefficients (PNa+, K+, m/s) of erythrocytes exists: Tls = 2.2×10-3 /PNa+, K+0.39 with corresponding coefficient R2=0.858. In different pathological conditions of red blood cells (hemolytic anemia, hereditary stomatocytosis, hereditary spherocytosis, hereditary elliptocytosis and thalasemias) the erythrocytes change the permeability coefficient as well as the lifespan, according to the same alometric relationship. [ABSTRACT FROM AUTHOR] |
