Hundreds of thousands of zombie randomised trials circulate among us.

Autor: Ioannidis, J. P. A.
Zdroj: Anaesthesia; Apr2021, Vol. 76 Issue 4, p444-447, 4p
Abstrakt: In the past, we have documented situations where fraudulent data were entered in a trial and this resulted in loss of trust not only in that trial itself but to the entire organisation running many trials [16]. Keywords: fabrication; individual patient data; randomised controlled trials; research misconduct; zombie EN fabrication individual patient data randomised controlled trials research misconduct zombie 444 447 4 03/04/21 20210401 NES 210401 In this issue, I Anaesthesia i , publishes an overview of the experience of the journal in trying to unearth submitted randomised controlled trials (RCT) that appear to be false and those where the data lack credibility so blatantly that they can be called "zombies" [1]. Of these six countries, only the USA (n = 147,442 trials) outperforms China (n = 54,746) in the number of trials entered in the WHO registry, and this includes trials registered over many years. [Extracted from the article]
Databáze: Complementary Index