An infant with localized vasoconstriction following topical propranolol exposure for infantile hemangioma.

Autor: Saerens, Julie, Gutermuth, Jan, Janmohamed, Sherief R.
Předmět:
Zdroj: Pediatric Dermatology; Jan2021, Vol. 38 Issue 1, p263-264, 2p
Abstrakt: We describe a 3‐month‐old child with an infantile hemangioma on the forehead with a blanched macule provoked by topical treatment with propranolol. This observation demonstrates that topically applied (non‐selective) beta‐blockers may induce blanched macules at the site of application, a side effect due to peripheral vasoconstriction of blood vessels by non‐selective beta‐2 blockade. This side effect was linked due to overuse and was reversible. This case illustrates the importance of providing thorough instructions regarding topical propranolol application. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index