Serum thymus and activation‐regulated chemokine (TARC/CCL17) may be useful to predict the disease activity in patients with bullous pemphigoid.

Autor: Suzuki, M., Yamaguchi, Y., Nakamura, K., Kanaoka, M., Matsukura, S., Takahashi, K., Takahashi, Y., Kambara, T., Aihara, M.
Předmět:
Zdroj: Journal of the European Academy of Dermatology & Venereology; Feb2021, Vol. 35 Issue 2, pe121-e124, 4p
Abstrakt: Serum thymus and activation-regulated chemokine (TARC/CCL17) may be useful to predict the disease activity in patients with bullous pemphigoid Bullous pemphigoid (BP) is one of the most common autoimmune bullous diseases that occasionally demonstrates relapse during the clinical course.1 However, the predictive markers for BP that are clinically equivalent to or more useful than the anti-BP180 Abs titre remain to be established.2,3 In this study, we analysed serum levels of multiple cytokines and TARC in BP patients to identify the predictive markers reflecting disease activity. Therefore, we further chronologically evaluated the fluctuation of TARC levels and anti-BP180 Abs titres on disease activity during the clinical course in 4 BP patients with relapse (Fig. [Extracted from the article]
Databáze: Complementary Index