| Autor: |
Juárez-González, Karina, Paredes-Cervantes, Vladimir, Gordillo-Rodríguez, Silvia, González-Guzmán, Saul, Moncayo-Valencia, Xochilt, Méndez-Martínez, Rocío, García-Carrancá, Alejandro, Martínez-Ezquerro, José Darío, Rivas-Ruiz, Rodolfo, Sánchez-Suárez, Patricia, Álvarez-Sandoval, Paola, Padilla-Arrieta, Patricia, Martínez-Salazar, Martha, Vázquez-Vega, Salvador |
| Předmět: |
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| Zdroj: |
Archives of Virology; Nov2020, Vol. 165 Issue 11, p2633-2640, 8p |
| Abstrakt: |
Our aim was to analyze the prevalence of high-risk human papillomavirus (HR-HPV) and its association with risk factors related to cervical lesions. We used 362 cervical samples from a transversal study to detect nineteen types from the high-risk HPV clade by highly sensitive PCR. Unexpectedly, we found a very high prevalence of HPV type 66 (32.8%), particularly in low-grade squamous intraepithelial lesions. A significant association of HPV66 with previously sexually transmitted disease was observed (p < 0.05). Our results strongly suggest that HPV66 might be indicative of cervical lesions that will not progress to cancer. HPV genotyping by methods that grouped type 66 with other HR-HPV clade types should be interpreted with caution. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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