| Autor: |
VHP, Leão, Aragão, MM, Pinho, RS, Hazin, AN, Paciorkowski, AR, Penalva de Oliveira, AC, Masruha, Marcelo Rodrigues |
| Zdroj: |
Current Neurology & Neuroscience Reports; Nov2020, Vol. 20 Issue 11, pN.PAG-N.PAG, 1p |
| Abstrakt: |
Purpose of Review: In 2016, the World Health Organization declared the Zika virus (ZIKV) outbreak a Public Health Emergency of International Concern following a cluster of associated neurological disorders and neonatal malformations. Our aim is to review the clinical and neuroimaging findings seen in congenital Zika syndrome. Recent Findings: ZIKV injures neural progenitor cells in the hippocampus, a brain region important for learning, memory, cognition, and emotion/stress response. Positron emission tomography has revealed global neuroinflammation in ZIKV infection in animal models. Summary: Congenital Zika syndrome is associated with a spectrum of brain abnormalities, including microcephaly, parenchymal calcifications, malformations of cortical development and defective neuronal migration, corpus callosum abnormalities, ventriculomegaly, and brainstem and cerebellar abnormalities. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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