| Abstrakt: |
In this study, the components of Moringa oleifera have been evaluated using Gas Chromatography–Mass Spectrometry. Infectious diseases a global burden and therefore prompting the need for the search of potential plants in the treatment of diseases. However, antibacterial activity of ethanol extract of Moringa oleifera, disc diffusion method was used to assess the effect of the extract on Proteus, Pseudomonas, Klebsiella and Escherichia coli, all the examined extract showed varying degrees of antibacterial activities against the selected pathogens. Highest inhibitory effect was observed in Proteus (16.95 mm) in concentration 500mg/ml, (16 mm) in concentration 100mg/ml and (14.7 mm) in concentration 250mg/ml followed by Pseudomonas (14.6mm) in concentration 500mg/ml, (13 mm) in concentration 100mg/ml and (11 mm) in concentration 250mg/ml, also in Proteus (10.34mm) in concentration 50mg/ml. Among this study, there are twenty seven major compounds were identified from Moringa oleifera extract by GC-MS. The compounds possess various potential health benefits. This study has shown that the ethanol extract of Moringa oleifera possess some degree of antimicrobial activity was less effective. However, efforts should be made to conduct in vivo studies with the extractsso as to confirm the present in vitro findings as zones of inhibition is not only affected. [ABSTRACT FROM AUTHOR] |
