The Impact of Active Intervention on the Spread of Penicillin-resistant Streptococcus pneumoniae in Swedish Day-care Centres.

Autor: Hogberg, Liselotte, Normark, Birgitta Henriques, Ringberg, Hakan, Stenqvist, Karin, Fredlund, Hans, Geli, Patricia, Grabowska, Katarzyna, Melander, Eva, Laurell, Martin, Ahren, Christina, Tornqvist, Eva, Falt, Rosmarie, Hoglund, Dag, Mollerberg, Gunnel, Ekdahl, Karl
Předmět:
Zdroj: Scandinavian Journal of Infectious Diseases; Sep2004, Vol. 36 Issue 9, p629-635, 7p
Abstrakt: Policies for handling cases of penicillin-non-susceptible Streptococcus pneumoniae (PNSP) in day-care groups vary between different counties in Sweden. The aim of this study was to evaluate the epidemiological effect of excluding PNSP-carriers from children's day-care centres (DCC). We followed the incidence in 14 DCC groups with ongoing PNSP-spread, by repeated group screens until no further cases could be identified. All identified carriers were excluded from DCC attendance in study area A (Skåne region) while they remained in the group in study area B (Göteborg and Örebro), according to local policies. The intervention effect was evaluated by comparing the number of additional cases after the baseline screen (start of the intervention period) between the 2 study areas. All PNSP-isolates were characterized by resistance pattern, serotype and pulse-field gel electrophoresis. The relative risk for children in DCCs without active intervention was 6.4 (95% CI: 2.0-20.7). Each prevented case in area A can be estimated to have demanded the exclusion of 2 other children from day care for approximately 4 weeks each. The total cost-benefit outcome of this action has to be seen in the light of the local situation with regard to the population prevalence and the distribution of other risk factors. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index