Effects of Hyperthermic Intraperitoneal MM-C Treatment with Radiotherapy on the Anastomotic Healing.

Autor: Avsar, F. M., Topaloglu, S., Arikan, B. U., Ozel, H., Sahin, M., Akmansu, M., Hengirmen, S., Pasaoglu, H.
Předmět:
Zdroj: European Surgical Research; May/Jun2004 Supplement 1, Vol. 36, p57-58, 2p
Abstrakt: Background: This study was designed to investigate the effects of hyperthermic intraperitoneal mitomycin-C (HIMMC) treatment plus preoperative radiotherapy on colonic healing. Anastomotic leak and mortality rates were significantly higher in HIMMC and radiotherapy (RT)+HIMMC groups compared to others. RT, HIMMC and their combination affected bursting pressures adversely. The lowest hydroxyproline levels were found in RT+HIMMC group. These data suggest that HIMMC treatment and its combination with preoperative radiotherapy have undesired side effects on colonic anastomosis.
Databáze: Complementary Index