Multicenter Study of Azole-Resistant Aspergillus fumigatus Clinical Isolates, Taiwan1.

Autor: Chi-Jung Wu, Wei-Lun Liu, Chih-Cheng Lai, Chien-Ming Chao, Wen-Chien Ko, Hsuan-Chen Wang, Ching-Tzu Dai, Ming-I Hsieh, Pui-Ching Choi, Jia-Ling Yang, Yee-Chun Chen, Wu, Chi-Jung, Liu, Wei-Lun, Lai, Chih-Cheng, Chao, Chien-Ming, Ko, Wen-Chien, Wang, Hsuan-Chen, Dai, Ching-Tzu, Hsieh, Ming-I, Choi, Pui-Ching
Předmět:
Zdroj: Emerging Infectious Diseases; Apr2020, Vol. 26 Issue 4, p806-809, 4p
Abstrakt: In a multicenter study, we determined a prevalence rate of 4% for azole-resistant Aspergillus fumigatus in Taiwan. Resistance emerged mainly from the environment (TR34/L98H, TR34/L98H/S297T/F495I, and TR46/Y121F/T289A mutations) but occasionally during azole treatment. A high mortality rate observed for azole-resistant aspergillosis necessitates diagnostic stewardship in healthcare and antifungal stewardship in the environment. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index