| Abstrakt: |
Rheumatoid arthritis (RA) affects about 1% of worlds population no population is immune but women are affected two to three times as often as men. The age on onset is between 30 and 55. RA is chronic inflammatory disease of the lining of the joint results in pain, stiffness, swelling, joint damage and loss of function of the joints. Inflammation most often affects the hands and feet. It tends to occur equally on both sides of the body. Medications have revolutionized modern-day treatment of RA, but many people also look to herbs and botanicals, substances from plants to manage their RA symptoms. The purpose of the present research work was to develop Topical Formulation for external application and evaluation of Polyhedral cream for the treatment of RA. Polyherbal cream formulation based on o/w base by using aqueous extract of Taraxacum (Dandelion), Curcuma longa (Turmeric), Zingiberofficinale (Ginger) with other effective ingredients cod liver oil and camphor. The prepared formulations (F1 to F5) were subjected to evaluation of different physicochemical parameters like Description/Appearance, spreadability, pH, Grittiness, Skin irritation test, Homogeneity. We observed that F2 formulation is passes in all parameter compare to other developed formulations. [ABSTRACT FROM AUTHOR] |
