| Autor: |
Sonoda, M., Balda, A. C., Otsuka, M., Gambale, W., Larsson, C. E. |
| Předmět: |
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| Zdroj: |
Veterinary Dermatology; Aug2004 Supplement 1, Vol. 15, p45-45, 1p |
| Abstrakt: |
The goal of this study was to evaluate the efficacy of lufenuron in the treatment of animals with dermatophytosis [ M. canis or M. gypseum ( n = 48) and T. rubrum ( n = 1)]. The study was performed over a 2-year period. The 49 animals (23 dogs and 26 cats) were randomly separated into four groups, each one receiving 50–120 mg/kg of lufenuron, divided into one to four doses administered at various intervals. Liver enzyme measurement were performed on all animals. The results showed clinical and mycological cure in 22–60% of the animals treated in the study, with the highest efficacy in the group treated with 120 mg/kg given in two doses at a 3-week interval (group IV). No systemic or cutaneous side effects or changes in liver enzyme levels were observed in any of the animals. Persian cats and Yorkshire terrier dogs had the highest rates of therapy failure. Lufenuron was more effective in dogs than cats. Morphological changes occurred in isolated Microsporum spp. colonies on culture. Funding: Self-funded. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
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