| Autor: |
Rija, Firas Faris, Mubarak Almahdawi, Zaid Mohmmed, Hussein, Sura Zahim |
| Zdroj: |
Indian Journal of Public Health Research & Development; Apr2019, Vol. 10 Issue 4, p1660-1665, 6p |
| Abstrakt: |
Metabolic bone disease (MBD) is a common complication of chronic kidney disease (CKD) and is a part of a broad spectrum of disorders of mineral metabolism that occur in this clinical setting and result in both skeletal and extraskletal consequences. This study was a cross sectional which conducted in Dialysis Unit in Tikrit Teaching Hospital in Tikrit city. The study started from January 2018 to August 2018 on study population age ranged from (18 - 68) years old The total of 60 subjects were separated to two groups as following: Control: This group consist of 30 healthy individuals (15 females and 15 males), and Hemodialysis (HD) (CKD) patients: This group consist of CKD 30 patients (15 females and 15 males). The results referred to the increased levels of Transforming growth factor-β (TGF-β), Osteoprogestrin (OPG), Sclerostin (SOST), Osteocalcin (OC) and C-reactive protein (CRP) in CKD with HD with highly significant differences (P≤0.01) when compared with control group. The bone metabolism biomarkers are increased in HD CKD patients who complicated to MBD. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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