| Autor: |
Bascoul, Simone, Cannat, Arlette, Huguet, Marie-France, Serre, Arlette |
| Předmět: |
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| Zdroj: |
Immunology; Aug78, Vol. 35 Issue 2, p213-221, 9p |
| Abstrakt: |
Mouse inoculation with three different phenol-insoluble fractions extracted from Brucella melitensis (fractions ‘PI’, ‘4A’ and ‘5’) induces an acceleration of the blood clearance of i.v. inoculated live Brucella and a diminution of the rate of multiplication of the injected bacteria in the spleen. Preincubation of the challenge inoculum in immune serum or i.p. injections of immune serum confer a good specific protection to non-immunized hosts. The results observed with fractionated sera suggest that, not only antibodies, but also other serum constituents may participate in the protective activity of immune sera. This is discussed in terms of the respective importance of humeral and cellular immunity to Brucella and of the choice of the best preparations for human or animal vaccination. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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