| Autor: |
Pitti, Robert M., Marsters, Scot A., Lawrence, David A., Roy, Margaret, Kischkel, Frank C., Dowd, Patrick, Huang, Arthur, Donahue, Christopher J., Sherwood, Steven W., Baldwin, Daryl T., Godowski, Paul J., Wood, William I., Gurney, Austin L., Hillan, Kenneth J., Cohen, Robert L., Goddard, Audrey D., Botstein, David, Ashkenazi, Avi |
| Předmět: |
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| Zdroj: |
Nature; 12/17/1998, Vol. 396 Issue 6712, p699, 5p, 2 Color Photographs, 3 Black and White Photographs, 1 Diagram, 11 Graphs |
| Abstrakt: |
Reports the discovery of a soluble decoy receptor, termed decoy receptor 3 (DcR3), that binds to Fas ligand (FasL) and inhibits FasL-induced apoptosis. How FasL is produced; Suggestion that certain tumors may escape FasL-dependent immune-cytotoxic attack by expressing a decoy receptor that blocks FasL. |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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