Direct Synthesis of N -Functionalized Dipropargylamine Linkers as Models for Use in Peptide Stapling.

Autor: Renzetti, Andrea, Rutherford, Ryan N., Fukumoto, Kozo, Kunciw, Dominique, Sore, Hannah F., Spring, David R.
Předmět:
Zdroj: Synlett; 2019, Vol. 30 Issue 19, p2153-2156, 4p
Abstrakt: N -Substituted dipropargylamines that are suitable as functionalized linkers for peptide stapling can be synthesized in one step under mild conditions from commercially available starting materials (41% to quantitative yield). [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index