| Autor: |
Кравченко, В. І., Чумак, А. А., Логановський, М., Дягіль, І. С., Кузьменко, В. Ф. |
| Předmět: |
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| Zdroj: |
Problems of Radiation Medicine & Radiobiology; 2017, Issue 22, p395-405, 11p |
| Abstrakt: |
A clinical case of the rituximab («Rituksim», «Mabthera») use to treat a man affected by the Chornobyl NPP acci& dent with malignant resistant form of myasthenia gravis in conjunction with chronic mixed infection by Toxoplasma, Epstein&Barr virus, Cytomegalovirus and Herpes simplex virus is described. In the dynamics of two&year's observa& tion the clinical efficacy of monoclonal antibodies was shown as the main symptoms stabilization and reducing doses of glucocorticoid and anticholinergic therapy. The positive effect was marked in the nearest and remote peri& ods. Taking to account the efficacy, safety and good tolerability of rituximab, it is advisable to recommend treat& ment for people exposed to ionizing radiation and developing myasthenia associated with chronic mixed infection by Toxoplasma, Epstein&Barr, Cytomegalovirus and Herpes simplex virus. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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