Improving Topical Microbicide Applicators for Use in Resource-Poor Settings.

Autor:	Vail, Janet G., Cohen, Jessica A., Kelly, Kimberly L.
Předmět:	CLINICAL trials CLINICAL medicine research MEDICAL research MEDICAL experimentation on humans EXPERIMENTAL medicine
Zdroj:	American Journal of Public Health; Jul2004, Vol. 94 Issue 7, p1089-1092, 4p, 1 Chart
Abstrakt:	With more than 60 potential microbicides being assessed in preclinical or clinical trials, most attention has been centered on products intended for topical application, with much less research conducted on the applicators that will be used to deliver the microbicides. However, applicator design relates to safety, efficacy, and acceptability. As the foundation for a more systematic approach to evaluating and possibly improving designs for topical microbicide applicators, we conducted a literature review and a series of interviews with microbicide developers, trial investigators, and trial sponsors. Our findings indicate that issues concerning applicator safety, reuse, and cost warrant further investigation. (Am J Public Health. 2004;94:1089-1092). [ABSTRACT FROM AUTHOR]
Databáze:	Complementary Index
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