| Autor: |
Steffen, Imke, Kai Lu, Yamamoto, Lauren K., Hoff, Nicole A., Mulembakani, Prime, Wemakoy, Emile O., Muyembe-Tamfum, Jean-Jacques, Ndembi, Nicaise, Brennan, Catherine A., Hackett Jr., John, Stramer, Susan L., Switzer, William M., Saragosti, Sentob, Mbensa, Guy O., Laperche, Syria, Rimoin, Anne W., Simmons, Graham, Lu, Kai, Hackett, John Jr |
| Předmět: |
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| Zdroj: |
Emerging Infectious Diseases; May2019, Vol. 25 Issue 5, p911-918, 18p |
| Abstrakt: |
We conducted a serologic survey of 2,430 serum samples collected during 1997-2012 for various studies to determine the prevalence of the hemorrhagic fever virus Ebola virus (EBOV) in equatorial Africa. We screened serum samples for neutralizing antibodies by using a pseudotype microneutralization assay and a newly developed luciferase immunoprecipitation system assay. Specimens seroreactive for EBOV were confirmed by using an ELISA. Our results suggest a serologic prevalence of 2%-3.5% in the Republic of the Congo and the Democratic Republic of the Congo, which have reported outbreaks of infection with EBOV. In addition we detected a seroprevalence of 1.3% in southern Cameroon, which indicated a low risk for exposure in this region. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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