| Autor: |
Mustafa, Alaa E. H., Sultan, Hesham A., Elshabrawy, Mona A., Abd Elghany, Mohammad E., Hakim, Ashraf S., Khalaf, Doaa D. |
| Předmět: |
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| Zdroj: |
Jordan Journal of Biological Sciences; Dec2018, Vol. 11 Issue 5, p549-555, 7p |
| Abstrakt: |
The present study is carried out to highlight the toxic effects of Aflatoxin B1 on humoral and cell-mediated immune responses of broilers, and to evaluate the efficacy of Mannan oligosaccharides (MOS) to ameliorate these toxic effects. In this study, experimental diets were designed, and the broiler chicks were divided into four groups. The first group was fed a normal diet. The second group was fed normal diet with MOS. The third group was fed aflatoxin B1 at the dose of (250 parts per billion"ppb"), while the last group was fed diet containing the aflatoxin in addition to MOS. The birds were checked for humoral and cell-mediated assays. The results revealed that there was a significant decreasing effect of 250 ppb AFB1 on both the antibody titer against the Newcastle disease virus (NDV) and lymphocyte blastogenesis and transformation. The investigation of differential leukocytic counts revealed lymphocytopenia and heterophilia. Dietary supplementation of a 1g MOS/Kg diet during aflatoxicosis could ameliorate some of the toxic effects of AFB1 in broilers, and improve the immune response. These outcomes confirm the immunosuppressive impact of aflatoxin and the role of mannan oligosaccharides to overcome its adverse effects. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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