| Autor: |
Majeed, Nadia Sadiq, Mohsen, Hanan Falah, Radhiyah Abdul Baqi Aldujaili |
| Předmět: |
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| Zdroj: |
Biochemical & Cellular Archives; 2018 Supplement, Vol. 18, p1107-1116, 10p |
| Abstrakt: |
Our work aimed for organic synthesis and biological investigation of some new heterocyclic derivatives by three steps : the first step included synthesis of some five-membered and six-membered heterocyclic derivatives (Pyrazole, Isoxazole, Oxazine and Thiazine) from Chalcone. The second step included synthesis of some 1,3-Oxazipene derivatives from Schiff's bases derived from Azo compound. The third step included the assay of biological activity of all compounds against four types of pathogens bacteria (Staphylococcus aureus, Granutice tella adiacens) gram positive and ( E. coli, Proteus mirabilis) gram negative the results exhibited excellent biological activity for all derivatives compared to antibiotics (Ampicillin and Ciprofloxacin). These compounds were identified and confirmed by FT- IR, 1HNMR, 13CNMR and elemental analysis. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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