| Autor: |
Sheikhpour, Elnaz, Sadri, Zahra, Heydari, Safiyehsadat, Ghanizadeh, Fatemeh, Zare-Zardini, Hadi, Atefi, Aref, Hashemi, Azam, Fallah, Tahereh, Ghiaspour, Esmat |
| Předmět: |
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| Zdroj: |
Iranian Journal of Pediatric Hematology & Oncology; 2018, Vol. 8 Issue 3, p180-186, 7p |
| Abstrakt: |
Vitamin D deficiency is known as the most common nutritional deficiency. It is created during infancy due to different factors, including decreased dietary intake, decreased dermal synthesis, malabsorption, enzymeinducing medications, and exclusive breastfeeding. Vitamin D deficiency is associated with poor bone health such as rickets and osteomalacia in children. Despite vitamin D plays an important role in bone health, its role in pediatric cancer is not detected and remained unknown; therefore, the aim of this study was to evaluate the role of vitamin D deficiency and its relation with cancer in children. Vitamin D in cancer children has been considered as a contributory factor for skeletal pathologies. Children with cancer may be at increased risk of vitamin D deficiency due to side effects which are induced by the disease and multiple treatments, given that chemotherapy and clinical radiation play a main role in decreased bone mineral density. Therefore, possible role of vitamin D deficiency in cancer pathogenesis and progression is well defined. It seems that these patients should be taken sufficient amount of calcium and vitamin D during chemotherapy and afterward. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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