| Autor: |
Zhai, Yi, Fang, Zhide |
| Předmět: |
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| Zdroj: |
Communications in Statistics: Theory & Methods; 8/15/2018, Vol. 47 Issue 16, p3803-3819, 17p |
| Abstrakt: |
We consider the problem of constructing static (or non sequential), approximate optimal designs for a class of dose-response models with continuous outcomes. We obtain conditions for a design being D-optimal or c-optimal. The designs are locally optimal in that they depend on the model parameters. The efficiency studies show that these designs have high efficiency when themis-specification of the initial values of model parameters is not severe. A case study indicates that using an optimal design may result in a significant saving of resources. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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