| Autor: |
Guangxin Yuan, Jia Fu, Liping An, Yan Zhuang, Yu Wang, Yunfeng Song, Zijing Qiao, Xiaolong Wang, Yufei Tian, Xiao Han, Peige Du, Guangyu Xu |
| Předmět: |
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| Zdroj: |
Clinical Laboratory; 2017, Issue 10, p1599-1606, 8p |
| Abstrakt: |
Background: About thirty thousand people globally die every day from infectious diarrhea, mostly caused by pathogenic Escherichia coli (E. coli) O157:H7. Methods: In order to search for clinical diagnostic biomarkers and novel drug targets for infectious diarrhea, we used a bibliometric method to collect pathogenic genes of E. coli O157:H7 and performed a functional analysis of the important pathogenic genes by pathway enrichment and operon analysis. Results: We found 364 pathogenic genes which may be involved in infection with E. coli O157:H7 including 50 new specific pathogenic genes. It is possible that these newly found pathogenic genes will be of great importance in the treatment of E. coli O157:H7 infected diseases and the discovery of novel diagnostic biomarkers. Conclusions: Our findings also lay a theoretical foundation for the control, diagnosis, and prognosis of pathogenic E. coli related diseases. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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