| Autor: |
SAHAF, RAKIA, NASEEM, NADIA, ANJUM, RABIA, AMAN-UR-REHMAN, NAGI, A. H. |
| Předmět: |
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| Zdroj: |
Pakistan Oral & Dental Journal; 3/31/2017, Vol. 37 Issue 1, p49-54, 6p |
| Abstrakt: |
Oral squamous cell carcinoma (OSCC) is one of the most prevalent malignant neoplasm worldwide and a major public health problem in Pakistan due to its high morbidity and poor survival rates. This study was designed to describe the clinic-pathological pattern of OSCC in the local population in terms of age, gender, site distribution, clinical presentation, histological subtype and histological grading. This descriptive study comprised of 57 cases with varied clinical profile, histological subtypes and grades of OSCC reporting at different hospitals in Lahore from Jan.2015-Sep.2015. Histological diagnosis and grading was carried out and were analyzed statistically. Mean age of the patients was 51.88 ±15.18 years and male to female ratio was 1.3:1. The commonest presenting complaint was non healing ulcer (49.1%).Tongue was the most frequently affected site (35.1%) followed by buccal mucosa (33.3%). Histologically, conventional SCC was the most prevalent subtype (89.5%) followed by papillary (5.3%) and verrucous(5.3%) carcinomas. Well differentiated carcinomas made most of the tumour burden (68.4%).Age vs. gender and histologic subtype vs. grade of OSCC was found to be significant (p=0.002, p=0.04). In our region most cases of well differentiated OSCC are reported with male preponderance. Early screening strategies are strongly suggested for reducing the mortality and morbidity associated with this debilitating disease. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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