| Abstrakt: |
A 4-week, open-label clinical trial, was conducted to evaluate the potential of Morinda citrifolia (noni) seed extract, in combination with other noni extracts, to improve skin quality. Two investigational products, containing noni ingredients, were applied daily for 4 weeks by 10 healthy, adult, volunteers. These contained noni seed concentrate as the major ingredient. Phytochemical analyses were also conducted on noni seed concentrate. Pre and post-test digital microscope images of the cheek revealed improvements in skin texture and brightness, less pigmentation, and reduction in red skin tone. Significant improvements also occurred in fine wrinkle, skin texture, skin clearness, skin spots, skin brightness and pore scores. The greatest impact was on skin clearness and pores, with respective average improvements of approximately 30% and 39%. Facial melanin concentration decreased by approximately 11%, with an accompanying 13% decline in erythema. Skin surface moisture increased by approximately 24%. The scopoletin concentration (mean ± standard error) of noni seed concentrate was 1.62 ± 0.20 mg/g, with 1.00 ± 0.24 mg/g ursolic acid and 69.33 ± 0.18 mg/g deacetylasperulosidic acid also being detected. The results substantiate the traditional uses of the noni plant for the improvement of skin health. The phytochemical analyses revealed the presence of biologically active compounds which likely explain the antiaging effects of these investigational products which contain noni seed extract. [ABSTRACT FROM AUTHOR] |
