Adrenal Hormone and Metabolic Biomarker Responses to 30 min of Intermittent Cycling Exercise in Breast Cancer Survivors.

Autor:	Evans, E. S., Hackney, A. C., Pebole, M. M., McMurray, R. G., Muss, H. B., Deal, A. M., Battaglini, C. L.
Předmět:	ADRENALINE BLOOD sugar BREAST tumors CANCER patients CARDIOPULMONARY system CYCLING EXERCISE EXERCISE physiology EXERCISE tests FATTY acids HEART beat HORMONES HYDROCORTISONE LACTATES LONGITUDINAL method NORADRENALINE PROBABILITY theory PULMONARY gas exchange RESEARCH RESEARCH funding STATISTICS PSYCHOLOGICAL stress TUMOR markers DATA analysis OXYGEN consumption ERGOMETRY DATA analysis software DESCRIPTIVE statistics MANN Whitney U Test
Zdroj:	International Journal of Sports Medicine; 2016, Vol. 37 Issue 12, p921-929, 9p
Abstrakt:	The aim of this study was to explore the effect of one bout of aerobic exercise on epinephrine, norepinephrine, cortisol, glucose, lactate, and free fatty acid (FFA) responses in breast cancer survivors and healthy controls. 9 female breast cancer survivors and 9 women without a history of cancer completed 30 min of cycle ergometry exercise at 60 % of VO2peak. Blood samples were taken preexercise, immediately post-exercise, and 2 h post-exercise from which plasma concentrations of study variables were measured. Immediately and 2 h post-exercise, increases were observed in epinephrine (control group only) norepinephrine (both groups), lactate (both groups), and FFA (both groups immediately post-exercise; breast cancer survivor group only at 2 h post-exercise) (p < 0.05). Cortisol decreased immediately and 2 h post-exercise in the control group while glucose decreased immediately post-exercise in the breast cancer survivor group (p < 0.05). In conclusion, breast cancer survivors appeared to display attenuated epinephrine, cortisol, and lactate responses while displaying larger magnitude changes in glucose and FFA responses compared to controls. These preliminary findings may have implications for the regulation of metabolism during exercise in breast cancer survivors. [ABSTRACT FROM AUTHOR]
Databáze:	Complementary Index
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