Drug induced exfoliative dermatitis: state of the art.

Autor: Yacoub, Mona-Rita, Berti, Alvise, Campochiaro, Corrado, Tombetti, Enrico, Ramirez, Giuseppe Alvise, Nico, Andrea, Di Leo, Elisabetta, Fantini, Paola, Sabbadini, Maria Grazia, Nettis, Eustachio, Colombo, Giselda
Zdroj: Clinical & Molecular Allergy; 8/22/2016, Vol. 14, p1-12, 12p, 1 Color Photograph, 1 Diagram, 3 Charts, 1 Graph
Abstrakt: Drug induced exfoliative dermatitis (ED) are a group of rare and severe drug hypersensitivity reactions (DHR) involving skin and usually occurring from days to several weeks after drug exposure. Erythema multiforme (EM), Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are the main clinical presentations of drug induced ED. Overall, T cells are the central player of these immune-mediated drug reactions. Here we provide a systematic review on frequency, risk factors, pathogenesis, clinical features and management of patients with drug induced ED. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index