Associations of GSTM1 ( del) and GSTP1 (Ile105Val) genetic polymorphisms and smoking in a family with congenital malformations.

Autor: Shatalina, I., Gareeva, Yu., Gordeeva, L., Voronina, E., Sutulina, I., Filipenko, M.
Zdroj: Russian Journal of Genetics: Applied Research; Mar2016, Vol. 6 Issue 2, p197-201, 5p
Abstrakt: The associations of polymorphisms of the GSTM1 ( del) and GSTP1 (Ile105Val) genes and smoking in a family with congenital malformations (CMs) in a newborn baby have been studied. The GSTM1 ( del) and GSTP1 (Ile105Val) gene polymorphisms themselves are not associated with the risk of CMs in a newborn. However, smoking in a family may increase the risk significance of the GSTP1 (Ile105Val) genotypes in the formation of CMs in a child. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index
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