Ultrasound-guided Percutaneous ethanol injection Protocol to Treat solid and Mixed Thyroid nodules.

Autor: Felício, João Soares, Conceição, Antônio Maria Silva, Santos, Flávia Marques, Sato, Michelle Masuyo Minami, de Arruda Bastos, Fabíola, de Souza, Ana Carolina Contente Braga, Koury, Camila Cavalcante, Neto, João Felício Abrahão, de Melo, Franciane Trindade Cunha, Carvalho, Carolina Tavares, Arbage, Thaís Pontes, de Figueiredo Junior, Antonio Bentes, de Rider Brito, Hana Andrade, Mourão Júnior, Marcelo Oliveira, de Souza Resende, Fabricio, Peixoto, Amanda Soares, Felício, Karem Miléo, Eijun Nishihara, Kyung Tae
Předmět:
Zdroj: Frontiers in Endocrinology; 6/6/2016, p1-6, 6p
Abstrakt: Context: Ultrasound (US)-guided percutaneous ethanol injection (PEI) has been proposed for treatment of benign thyroid nodules (TNs). However, there is no consensus for the optimal amount of ethanol injection, number of applications, and time to re-evaluation in order to achieve maximum volume reduction with minimum adverse effects. Objective: The purpose of the present study was to analyze the effectiveness of an US-guided PEI protocol to treat solid and mixed TNs based on a new target outcome. Patients and methods: We performed a prospective study evaluating the results of PEI in 52 patients with benign solid and mixed TNs. The ethanol dose was fixed in 30% of the nodular volume per session. Patients returned 1 month after each session for US re-evaluation. Therapeutic success was defined as volume reduction of at least 30% associated with disappearance of clinical symptoms and a complete esthetic satisfaction reported by the patient. Conclusion: Our protocol is effective and safe to treat solid and mixed benign TNs based on our established outcome. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index