| Autor: |
Hamza, Hala Salah, Gaber, Khaled Ramzy, Raouf, Wessam Abdel, Dohain, Ahmed Mohamed, Abdel Mohsen, Gaser Sayed, Abdd Elfattah, Ahmed Nabil, Senousy, Sameh Mohammed, Abozid, Heba E., Attia, Wael Ahmed |
| Předmět: |
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| Zdroj: |
Journal of Clinical Neonatology; Jan-Mar2016, Vol. 5 Issue 1, p35-38, 4p |
| Abstrakt: |
Background: Fetal echocardiography (FE) has contributed in early identification of serious conotruncal anomalies that require early intervention in postnatal life. Objective: Our study aims to evaluate the incidence of development of conotruncal anomalies in pregnant women with high-risk pregnancies referred for extended FE. Subjects and Methods: One hundred and fifty-one pregnant mothers were referred between 2013 and 2014, from the feto-maternal clinic for FE in a pediatric cardiology unit, as they had risk factors for developing fetal cardiac anomalies. Results: Consanguineous marriage was reported in 62% of cases. Twelve studies (7.9%) showed abnormal cardiac examination, nine of which were outcomes of consanguineous marriage. Two cases had Ebstein anomaly; both cases were outcomes of consanguineous marriage, in one of them the mother received Aspirin during the 1st trimester. Another two cases were diagnosed as a muscular ventricular septal defect, one had a family history of congenital heart defects and was the outcome of consanguineous marriage, the other had a history of Aspirin administration during the 1st trimester and nonconsanguineous marriage, only one case had hypoplastic left heart syndrome, and the maternal age was 36 years. Six cases (3.9%) had fetuses with conotruncal anomalies; all were outcomes of consanguineous marriage. Conclusions: FE is valuable in early detection of serious defects as conotruncal anomalies that may require early peri-natal intervention, especially in cases with high risk. Positive consanguinity is a major problem in developing countries, possibly associated with serious problems in offspring. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
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