Phase 1 study of galunisertib, a TGF-beta receptor I kinase inhibitor, in Japanese patients with advanced solid tumors.
Autor: | Fujiwara, Yutaka, Nokihara, Hiroshi, Yamada, Yasuhide, Yamamoto, Noboru, Sunami, Kuniko, Utsumi, Hirofumi, Asou, Hiroya, TakahashI, Osamu, Ogasawara, Ken, Gueorguieva, Ivelina, Tamura, Tomohide |
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Předmět: |
TRANSFORMING growth factors-beta
KINASE inhibitors JAPANESE people ANTINEOPLASTIC agents DRUG dosage DISEASES ASIANS BIOTRANSFORMATION (Metabolism) CELL receptors CLINICAL trials COMPARATIVE studies CONSTIPATION DOSE-effect relationship in pharmacology EXANTHEMA HETEROCYCLIC compounds INSOMNIA RESEARCH methodology MEDICAL cooperation PHARMACOKINETICS QUINOLINE RESEARCH TRANSFERASES TUMORS EVALUATION research TREATMENT effectiveness THERAPEUTICS |
Zdroj: | Cancer Chemotherapy & Pharmacology; Dec2015, Vol. 76 Issue 6, p1143-1152, 10p |
Abstrakt: | |
Databáze: | Complementary Index |
Externí odkaz: |