| Autor: |
Bedalov, Antonio, Hirao, Maki, Posakony, Jeffrey, Nelson, Melisa, Simon, Julian A. |
| Předmět: |
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| Zdroj: |
Molecular & Cellular Biology; Oct2003, Vol. 23 Issue 19, p7044-7054, 11p, 5 Diagrams, 2 Charts, 10 Graphs |
| Abstrakt: |
Identifies factors that regulate cellular levels of nicotine adenine dinucleotide (NAD)[sup +]. Finding that the homologue of Sir2p, Hst1p is an NAD[sup +]-dependent deacetylase with relatively low affinity for NAD[sup +] that functions as a cellular NAD [sup +] sensor to repress the NAD[sup +] biosynthesis program when NAD[sup +] levels are adequate in Saccharomyces cerevisaie. |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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