| Autor: |
Won, Yu-Mi, Seong, Zuh-Kyung, Kim, Jae-Lim, Kim, Hui-Seong, Song, Hyuk-Hwan, Kim, Doo-Young, Kim, Jung-Hee, Oh, Sei-Ryang, Cho, Hyun-Woo, Cho, Jung-Hee, Lee, Hyeong-Kyu |
| Zdroj: |
Archives of Pharmacal Research; Aug2015, Vol. 38 Issue 8, p1541-1551, 11p |
| Abstrakt: |
Three new triterpene glycosides (Lonicerosides K, L and M) and 11 known compounds were isolated from the aerial parts of Weigela subsessilis. Among the known isolated compounds, loniceroside A, sweroside, kaempferol-3- O-glucopyranoside 6″-(3-hydroxy-3-methylglutarate), kaempferol-3- O-acetylglucoside and grandifloroside were reported for the first time in a Weigela genus plant. Their chemical structures were identified using extensive spectroscopic analysis including two-dimensional (2D)-NMR experiments, HR-ESI-QTOF-MS and comparison with reported data. Among these compounds, lonicerosides A and L had potent melanogenesis stimulatory activity in murine B16F0 melanoma cells. The structural relationship of active compounds was discussed. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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