| Autor: |
Philpot, Michael, Treloar, Adrian, Saiz, Anna, Croonen, Heidi |
| Předmět: |
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| Zdroj: |
International Journal of Psychiatry in Clinical Practice; Sep2003, Vol. 7 Issue 3, p205, 7p |
| Abstrakt: |
INTRODUCTION It has been suggested that selective serotonin reuptake inhibitors (SSRI) may lengthen ECT-induced seizures but may be more effective than tricyclic antidepressants (TCA) in preventing relapse following ECT. The present study attempted to determine the effects of concurrent psychotropic medication on ECT seizure duration, treatment response and time to readmission. METHOD Retrospective case note study of 70 depressed patients receiving bilateral ECT during a 4-year period at a single ECT unit. RESULTS Antidepressant class had no effect on seizure duration, immediate outcome, time to readmission or further ECT; no patients had prolonged seizures; readmission was less likely in patients whose antidepressant class was changed after ECT than in those continuing on the same drugs (median survival of 102 and 37 weeks respectively, P=0.0050). Patients with a poorer long-term outcome were more likely to be prescribed combined antidepressants/lithium or anticonvulsants in the continuation phase (P=0.0017) and have been treated with higher ECT doses (P=0.0021). CONCLUSION The use of concurrent antidepressants has no major clinical influence on seizure duration or response to ECT. However, changing the pharmacotherapy regime post-ECT may improve prognosis. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
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