| Autor: |
TAMANG, HEM KUMAR, TIMILSINA, UDDHAV, SINGH, KHELANAND PRASAD, SHRESTHA, SANJIT, RAMAN, RAMENDRA KUMAR, PANTA, PUJAN, KARNA, PREETI, KHADKA, LAXMI, DAHAL, CHANDIKA |
| Předmět: |
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| Zdroj: |
Journal of Clinical & Diagnostic Research; Feb2014, Vol. 8 Issue 2, p34-36, 3p |
| Abstrakt: |
Apo B and Apo A-I, are structural and functional components of lipoprotein particles that serve as transporters of cholesterol. The apo B/apo A-I ratio reflects the cholesterol transport and has been shown to be strongly related to risk of Myocardial infarction, stroke and other Cardiovascular manifestations. Materials and Methods: Forty five participants with Cardiovascular Disease (CVD) and forty four healthy participants were included from different locations of Kathmandu valley, Nepal. Fasting blood samples were collected from ante-cubital vein and serum samples were used for lipid parameters, apo B and apo A-I levels measurement. Results: Statistically significant differences were found for apo B/apo A-I ratio, HDL-c and apo B between the groups. The other lipid parameters and lipid ratios such as total cholesterol, triglyceride, low density lipoprotein, TC/HDL-c, TG/HDL-c and LDL-c/HDL-c were not found to be significant. Conclusion: Apo B/apo A-I ratio seems to have better predictive value than that of classical lipid parameters in cardiovascular risk assessment. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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