[Prevalence of discrepant lipid levels in Curaçao].

Autor: Leerink CB; Afd. Klinische Chemie en Hematologie, Willemstad, Curaçao, Laboratorium voor de Volksgezondheid van de Nederlandse Antillen., Gerstenbluth I
Jazyk: Dutch; Flemish
Zdroj: Nederlands tijdschrift voor geneeskunde [Ned Tijdschr Geneeskd] 1997 Dec 20; Vol. 141 (51), pp. 2488-92.
Abstrakt: Objective: To assess the prevalence of lipid risk factors in Curaçao and to investigate possible interactions with socioeconomic and demographic variables.
Design: Cross-sectional population-based study.
Setting: Public Health Laboratory and Public Health Service, Curaçao, Netherlands Antilles.
Methods: In a random sample of persons aged 18 years and over from the population of Curaao, serum levels were measured of total cholesterol, high-density lipoprotein (HDL) cholesterol, triglycerides and, in a smaller number of samples, of lipoprotein(a) (Lp(a)). The findings were in persons between 20 and 60 years compared with those reported for a random sample from the Netherlands. Multiple regression analysis was used to study the relationship between the total cholesterol values found and various socio-economic variables (age, sex, education, place of residence, race).
Results: Among persons aged 20-59 years serum cholesterol levels were > 6.5 mmol/l in 30 of the 288 male participants (11%) and in 42 of the 427 female participants (10%). Fifty-three of the males (18%) had HDL cholesterol levels < 0.9 mmol/l as against 31 of the females (7%). The distributions of both total cholesterol and HDL cholesterol levels was better in Curaao than in the Netherlands, among males aged 20-29 years and males and females over 40 years of age. The median Lp(a) concentration of the 225 participants of Curaao in whom it was measured was 250 mg/l, as against 80 mg/l in the Dutch group. More advanced age, female sex, higher educational level, negroid race and residence in the 'East District' were correlated with a higher serum level of total cholesterol.
Conclusions: Both total cholesterol and HDL cholesterol concentrations were favourable in Curaçao compared with the Netherlands, especially in the elderly population.
Databáze: MEDLINE