[Conservation of erythrocyte transfusion media after removal of leukocytes by filtration].

Autor: Mel'nikova VN, Pleshakova VT, Selivanov EA, Beliaeva ZP, Vorob'eva TIu, Afanas'ev VK, Lozina NN
Jazyk: ruština
Zdroj: Gematologiia i transfuziologiia [Gematol Transfuziol] 1994 Jan-Feb; Vol. 39 (1), pp. 17-21.
Abstrakt: Preserved whole blood and erythrocyte suspension in the colloid preservative "Modezhele" were studied after leukocyte filtration through newly designed leukofilter. Morphofunctional properties of erythrocytes from the filtered media remained much more potent than from the nonfiltered ones throughout 18 months of the follow-up. The filtered media exhibited good rheology and were free of microclots. It is suggested that a favourable effect of leukocyte elimination in conservation of erythrocytic media may result from inhibited activity of leukocytic enzymes, primarily, proteolytic.
Databáze: MEDLINE